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Pharmacological enhancers of autophagy such as rapamycin and metformin, act broadly on this system, while more targeted strategies, such as urolithin A to stimulate mitophagy, are under active investigation [256, 257]

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Integration of phytochemistry with nanomedicine is also suggested to develop a more targeted and efficacious therapy using phytochemicals to provide uroprotective effects in weakening the inflammatory sequelae in interstitial cystitis